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Frontiers Do no harm: managing nausea and vomiting in GLP 1 based obesity therapies Switching from Semaglutide to Tirzapetide Dosing : r tirzepatidecompound PDF] Effect of Additional Oral Semaglutide vs Sitagliptin on Glycated Hemoglobin in Adults With Type 2 Diabetes Uncontrolled With Metformin Alone or With Sulfonylurea: The PIONEER 3 Randomized Clinical Trial Semantic Scholar Semaglutide (Month 1) 0.25mg CITIZEN MEDS semaglutide and resting heart rate I trialed micro dosing tirzepatide for its potential longevity benefits and it increased my RHR by 3 bpm. GLP 1RAs, such as semaglutide, liraglutide, and tirzepatide, elevate resting
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4.8 ★★★★★
Based on 470 reviews
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Product Reviews
★★★★★ 1
Difficult to use and eventually hose end broke
Size: 24oz, Size: 24oz
I purchased this can of Fix-A-Flat to fix, what I believe, is a rim leak on my truck tire which needs to be filled once every week or so. When I attempted to use the product I let some air out of the tire (down to 25 psi) so it would be easier to dispense the contents. The instructions on the can say to have the valve on the tire at the 6 o'clock...which I did as well.
When I attempted to make the connection using the swivel connector on the can's hose it was difficult. The hose on the can is very short and stiff and because it came coiled in the can's lid, did not want to straighten out making connecting it to the tire a very awkward process. It was hard to screw the hose end on the valve without it binding so it felt like it was cross-threading. I have machined aluminum valve caps and they go one very easily so I know the threads on the tire's valve stem are clean.
I finally did get it on and when I attempted to dispense the contents it filled the hose but that was about it. I could not see any contents flowing thru the hose at all. I assumed it was not on far enough so I took it off to try again and the contents sprayed everywhere showing it was indeed under pressure....just not going into the tire. After multiple tries the hose end eventually just broke off and stayed on the tire's valve stem. I was able to get it off, but at this point the can is useless to me.
Obviously I cannot and will not recommend this product. I have used this product before and had success, but that was when the hose was longer and wired to the side of the can making it much easier to use, versus how they are shipped now. I would recommend going with another product or possible going to a box store (which is what I plan to do) to find one that does not have this design. At the very least, if you do choose to disregard this review, I would try it with the tire's valve stem at the 3 or 9 o'clock position which might make it easier to thread the hose end on to the valve stem,.
Also, if you choose to go this route you might just be throwing your money away. I attempted to get a refund from Amazon and was directed to the manufacture's web site. From there you are directed to use the 800 number of leave a general message that is in no way connected to your Amazon purchase. Past experience tells me it will not be an easy process so it looks like I am out the $12.
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Reviewed in the United States on March 10, 2024
★★★★★ 5
This is a necessity for anyone that tries a car!!
Size: 20oz 6pk
I haven’t used this yet, but I bought a case to give to my family members. My friend who came outside to a flat tire. It was a Sunday in Utah so there was really no one that could fix it. Walmart told her to get this product. She had to drive home immediately following using this product (300 miles) It has been over two months now and my niece is still driving on that tire. It was a brand new tire that was costly so she decided to just wait and see how long this product will work. Great gift for anyone in the family that drives. This does not work on a blown tire. If you wake up in the morning and your tire is flat, or you get out of class and your tire is flat, just use this product and no calls need to be made.
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Reviewed in the United States on October 14, 2025
★★★★★ 5
Great product and great service
Size: 16oz
By all accounts it's a great product! It arrived and I feel more confident having it with me in the car.
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Reviewed in the United States on April 28, 2026
★★★★★ 5
Essential Emergency Kit That Every Vehicle Should Have
After experiencing a flat tire on a remote highway late at night, I realized how unprepared I was for roadside emergencies. That experience led me to purchase the AUTOWN Flat Tire Repair Kit, and I'm incredibly grateful to now have this comprehensive solution in my vehicle. This kit has already saved me twice from having to call for expensive roadside assistance, and the peace of mind it provides is absolutely priceless.
The 31-piece kit is impressively complete. It includes everything you need to handle a flat tire emergency, from the tire plugs themselves to insertion tools, rasps, and even extras that many cheaper kits omit. The variety of plug sizes means you can handle different types of punctures, and having multiple plugs means you're prepared for more than one emergency before needing to restock.
What sets this kit apart is the quality of the tools. The T-handle insertion tool feels solid and well-made, not like the flimsy plastic tools that come with some budget kits. The reamer tool cuts through damaged rubber cleanly and efficiently, making it easy to prepare the puncture hole for the plug. Having used cheaper tire repair kits in the past that broke during use, I really appreciate the durability and reliability of these tools.
The storage case is another thoughtful feature that makes this kit practical for vehicle storage. Everything fits neatly in the organized case with dedicated spaces for each component, which means you can quickly find what you need during an emergency. The case is compact enough to fit in a glove box or under a seat, but it's also rugged enough to withstand being rattled around in a trunk without falling apart.
Using this kit is surprisingly straightforward, even for someone without extensive automotive experience. The process involves identifying the puncture, using the reamer to prepare the hole, inserting the plug with the T-handle tool, and trimming the excess. I was able to successfully repair a puncture on my first attempt following the basic instructions, and the repair has held perfectly for months of daily driving.
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Reviewed in the United States on February 2, 2026
★★★★★ 5
Complete and very handy tire repair kit
I bought this tire repair kit to keep in my vehicle for emergencies, and it has already come in handy. The kit comes with everything needed to fix a flat quickly, and having all the tools in one case is very convenient.
The plugs worked well and sealed the puncture properly, allowing me to get back on the road without issues. The tools feel solid and easy to use, even if you don’t have a lot of experience with tire repairs.
The case is a bit tight once everything is packed back in, but that’s a small issue. Overall, this is a reliable and practical kit that’s great to have for cars, motorcycles, or other vehicles. I’m very glad I bought it.
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Reviewed in the United States on February 2, 2026
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